Endothelin-1 signaling maintains glial progenitor proliferation in the postnatal subventricular zone

Endothelin-1 (ET-1) is a vasoconstrictor molecule that is also present in the developing and injured CNS. Here the authors show that ET-1 is present in the postnatal subventricular zone and acts to regulate maintenance and proliferation of radial glial cells and oligodendrocyte progenitor cells.

Bibliographic Details
Main Authors: Katrina L. Adams, Giulia Riparini, Payal Banerjee, Marjolein Breur, Marianna Bugiani, Vittorio Gallo
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16028-8