Visual Attention Deficits in Schizophrenia Can Arise From Inhibitory Dysfunction in Thalamus or Cortex

Visual Attention Deficits in Schizophrenia Can Arise From Inhibitory Dysfunction in Thalamus or Cortex

Schizophrenia is associated with diverse cognitive deficits, including disorders of attention-related oculomotor behavior. At the structural level, schizophrenia is associated with abnormal inhibitory control in the circuit linking cortex and thalamus. We developed a spiking neural network model tha...

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Bibliographic Details
Main Authors: Yohan J. John, Basilis Zikopoulos, Daniel Bullock, Helen Barbas
Format: Article
Language:English
Published: The MIT Press 2018-12-01
Series:Computational Psychiatry
Subjects:
psychiatry
thalamic reticular nucleus
computational model
spiking
GABA
NMDA
parvalbumin neurons
calbindin neurons
disinhibition
Online Access:https://www.mitpressjournals.org/doi/pdf/10.1162/cpsy_a_00023

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https://www.mitpressjournals.org/doi/pdf/10.1162/cpsy_a_00023

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