Serine Protease from <i>Nereis virens</i> Inhibits H1299 Lung Cancer Cell Proliferation via the PI3K/AKT/mTOR Pathway

This study explores the in vitro anti-proliferative mechanism between Nereis Active Protease (NAP) and human lung cancer H1299 cells. Colony formation and migration of cells were significantly lowered, following NAP treatment. Flow cytometry results suggested that NAP-induced growth inhibition of H1...

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Bibliographic Details
Main Authors: Yanan Chen, Yunping Tang, Yanhua Tang, Zuisu Yang, Guofang Ding
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/17/6/366