HP1γ Sensitizes Cervical Cancer Cells to Cisplatin through the Suppression of UBE2L3

Cisplatin is the most frequently used agent for chemotherapy against cervical cancer. However, recurrent use of cisplatin induces resistance, representing a major hurdle in the treatment of cervical cancer. Our previous study revealed that HP1γ suppresses UBE2L3, an E2 ubiquitin conjugating enzyme,...

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Bibliographic Details
Main Authors: Sang Ah Yi, Go Woon Kim, Jung Yoo, Jeung-Whan Han, So Hee Kwon
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
p53
Online Access:https://www.mdpi.com/1422-0067/21/17/5976