Divergent axial morphogenesis and early shh expression in vertebrate prospective floor plate

Abstract Background The notochord has organizer properties and is required for floor plate induction and dorsoventral patterning of the neural tube. This activity has been attributed to sonic hedgehog (shh) signaling, which originates in the notochord, forms a gradient, and autoinduces shh expressio...

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Bibliographic Details
Main Authors: Stanislav Kremnyov, Kristine Henningfeld, Christoph Viebahn, Nikoloz Tsikolia
Format: Article
Language:English
Published: BMC 2018-01-01
Series:EvoDevo
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13227-017-0090-x