Divergent axial morphogenesis and early shh expression in vertebrate prospective floor plate
Abstract Background The notochord has organizer properties and is required for floor plate induction and dorsoventral patterning of the neural tube. This activity has been attributed to sonic hedgehog (shh) signaling, which originates in the notochord, forms a gradient, and autoinduces shh expressio...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-01-01
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Series: | EvoDevo |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13227-017-0090-x |