Discovery of New Potent anti-MERS CoV Fusion Inhibitors

Discovery of New Potent anti-MERS CoV Fusion Inhibitors

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...

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Bibliographic Details
Main Authors: Mahmoud Kandeel, Mizuki Yamamoto, Byoung Kwon Park, Abdulla Al-Taher, Aya Watanabe, Jin Gohda, Yasushi Kawaguchi, Kentaro Oh-hashi, Hyung-Joo Kwon, Jun-ichiro Inoue
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
coronavirus
MERS-CoV
fusion inhibitors
antivirals
drug discovery
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.685161/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.685161/full

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