Oral beta-glucan adjuvant therapy converts nonprotective Th2 response to protective Th1 cell-mediated immune response in mammary tumor-bearing mice.
Beta (1-3)-D-glucans were identified almost 40 years ago as biological response modifiers that stimulated tumor rejection. In vitro studies have shown that beta-glucans bind to a lectin domain within complement receptor type 3 (CR3), or to, more recently described dectin-1 a beta-glucan specific rec...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Via Medica
2007-06-01
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Series: | Folia Histochemica et Cytobiologica |
Online Access: | http://czasopisma.viamedica.pl/fhc/article/view/4540 |