Oral beta-glucan adjuvant therapy converts nonprotective Th2 response to protective Th1 cell-mediated immune response in mammary tumor-bearing mice.

Beta (1-3)-D-glucans were identified almost 40 years ago as biological response modifiers that stimulated tumor rejection. In vitro studies have shown that beta-glucans bind to a lectin domain within complement receptor type 3 (CR3), or to, more recently described dectin-1 a beta-glucan specific rec...

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Bibliographic Details
Main Authors: Gordon D Ross, Feng Hong, Daniel J Allendorf, Jarek Baran
Format: Article
Language:English
Published: Via Medica 2007-06-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4540