Carvedilol Attenuates Inflammatory-Mediated Cardiotoxicity in Daunorubicin-Induced Rats

Carvedilol Attenuates Inflammatory-Mediated Cardiotoxicity in Daunorubicin-Induced Rats

Cardiotoxicity, which results from intense cardiac oxidative stress and inflammation, is the main limiting factor of the anthracyclines. Carvedilol, a beta blocker that is used as a multifunctional neurohormonal antagonist, has been shown to act not only as an anti-oxidant, but also as an anti-infla...

Full description

Bibliographic Details
Main Authors: Punniyakoti T. Veeravedu, Makoto Kodama, Vivian Soetikno, Kenji Suzuki, Rajarajan A. Thandavarayan, Kenichi Watanabe, Flori R. Sari, Wawaimuli Arozal, Somasundaram Arumugam, Meilei Harima
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:Pharmaceuticals
Subjects:
daunorubicin
carvedilol
inflammation
fibrosis
Online Access:http://www.mdpi.com/1424-8247/4/3/551/

Internet

http://www.mdpi.com/1424-8247/4/3/551/

Similar Items