Targeting Telomerase and ATRX/DAXX Inducing Tumor Senescence and Apoptosis in the Malignant Glioma

Targeting Telomerase and ATRX/DAXX Inducing Tumor Senescence and Apoptosis in the Malignant Glioma

Glioblastoma multiforme (GBM) is a type of brain tumor that is notorious for its aggressiveness and invasiveness, and the complete removal of GBM is still not possible, even with advanced diagnostic strategies and extensive therapeutic plans. Its dismal prognosis and short survival time after diagno...

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Bibliographic Details
Main Authors: Hueng-Chuen Fan, Chuan-Mu Chen, Ching-Shiang Chi, Jeng-Dau Tsai, Kuo-Liang Chiang, Yu-Kang Chang, Shinn-Zong Lin, Horng-Jyh Harn
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma multiforme (GBM) 2
telomerase 3
alternative lengthening of telomeres 4
α-thalassemia/mental retardation syndrome X-linked protein (ATRX) 5
death-domain associated protein (DAXX) 5
butylidene phthalide (BP)
Online Access:http://www.mdpi.com/1422-0067/20/1/200

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http://www.mdpi.com/1422-0067/20/1/200

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