Retinal ganglion cell dysfunction in mice following acute intraocular pressure is exacerbated by P2X7 receptor knockout

Abstract There is increasing evidence for the vulnerability of specific retinal ganglion cell (RGC) types in those with glaucoma and in animal models. In addition, the P2X7-receptor (P2X7-R) has been suggested to contribute to RGC death following stimulation and elevated IOP, though its role in RGC...

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Bibliographic Details
Main Authors: Anna Y. M. Wang, Vickie H. Y. Wong, Pei Ying Lee, Bang V. Bui, Stefanie Dudczig, Kirstan A. Vessey, Erica L. Fletcher
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83669-0