Hypogonadal hypertension in male Sprague-Dawley rats is renin-angiotensin system-dependent: role of endogenous androgens

Abstract Background Acutely, testosterone (TES) and other androgens are efficacious vasodilators, both in vitro and in vivo; however, their long-term effects on arterial blood pressure (BP) remain unclear. It was hypothesized that endogenous androgens exert long-term anti-hypertensive effects on sys...

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Bibliographic Details
Main Authors: Andrea E. Hanson, Mercedes Perusquia, John N. Stallone
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Biology of Sex Differences
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13293-020-00324-5