Influence of pentraxin 3 (PTX3) genetic variants on myocardial infarction risk and PTX3 plasma levels.

PTX3 is a long pentraxin of the innate immune system produced by different cell types (mononuclear phagocytes, dendritic cells, fibroblasts and endothelial cells) at the inflammatory site. It appears to have a cardiovascular protective function by acting on the immune-inflammatory balance in the car...

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Bibliographic Details
Main Authors: Elisa Barbati, Claudia Specchia, Massimo Villella, Marco Luciano Rossi, Simona Barlera, Barbara Bottazzi, Luisa Crociati, Carmela d'Arienzo, Raffaele Fanelli, Cecilia Garlanda, Francesca Gori, Ruggiero Mango, Alberto Mantovani, Giuseppe Merla, Enrico B Nicolis, Silvia Pietri, Patrizia Presbitero, Yukio Sudo, Alessandro Villella, Maria Grazia Franzosi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3532160?pdf=render