Examination of genome homogeneity in prokaryotes using genomic signatures.

BACKGROUND:DNA word frequencies, normalized for genomic AT content, are remarkably stable within prokaryotic genomes and are therefore said to reflect a "genomic signature." The genomic signatures can be used to phylogenetically classify organisms from arbitrary sampled DNA. Genomic signat...

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Bibliographic Details
Main Authors: Jon Bohlin, Eystein Skjerve
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2781299?pdf=render