Compensatory responses induced by oxidative stress in Alzheimer disease

Oxidative stress occurs early in the progression of Alzheimer disease, significantly before the development of the pathologic hallmarks, neurofibrillary tangles and senile plaques. In the first stage of development of the disease, amyloid-β deposition and hyperphosphorylated tau function as...

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Bibliographic Details
Main Authors: PAULA I MOREIRA, XIONGWEI ZHU, QUAN LIU, KAZUHIRO HONDA, SANDRA L SIEDLAK, PEGGY L HARRIS, MARK A. SMITH, GEORGE PERRY
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000100002