Whole Exome Sequencing of Extreme Morbid Obesity Patients: Translational Implications for Obesity and Related Disorders

Whole Exome Sequencing of Extreme Morbid Obesity Patients: Translational Implications for Obesity and Related Disorders

Whole-exome sequencing (WES) is a new tool that allows the rapid, inexpensive and accurate exploration of Mendelian and complex diseases, such as obesity. To identify sequence variants associated with obesity, we performed WES of family trios of one male teenager and one female child with severe ear...

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Bibliographic Details
Main Authors: Gilberto Paz-Filho, Margaret C.S. Boguszewski, Claudio A. Mastronardi, Hardip R. Patel, Angad S. Johar, Aaron Chuah, Gavin A. Huttley, Cesar L. Boguszewski, Ma-Li Wong, Mauricio Arcos-Burgos, Julio Licinio
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Genes
Subjects:
DNAAF1
genetics
leptin-melanocortin
LRP2
megalin
monogenic
obesity
pituitary
UCP2
whole-exome sequencing
Online Access:http://www.mdpi.com/2073-4425/5/3/709

Internet

http://www.mdpi.com/2073-4425/5/3/709

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