Comparative Immunogenomics of Canine Natural Killer Cells as Immunotherapy Target

Comparative Immunogenomics of Canine Natural Killer Cells as Immunotherapy Target

Natural killer (NK) cells are key effectors of the innate immune system, but major differences between human and murine NK cells have impeded translation. Outbred dogs offer an important link for studies of NK biology and immunotherapy. We analyzed gene expression of putative NK populations from hea...

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Bibliographic Details
Main Authors: Alicia A. Gingrich, Taylor E. Reiter, Sean J. Judge, Daniel York, Mio Yanagisawa, Aryana Razmara, Ian Sturgill, Ugur Nur Basmaci, Rachel V. Brady, Kevin Stoffel, William J. Murphy, Robert B. Rebhun, C. Titus Brown, Robert J. Canter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
natural killer cells
comparative oncology
single cell
immunotherapy, osteosarcoma
canine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.670309/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.670309/full

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