BET protein inhibition regulates cytokine production and promotes neuroprotection after spinal cord injury

BET protein inhibition regulates cytokine production and promotes neuroprotection after spinal cord injury

Abstract Background Spinal cord injury (SCI) usually causes a devastating lifelong disability for patients. After a traumatic lesion, disruption of the blood-spinal cord barrier induces the infiltration of macrophages into the lesion site and the activation of resident glial cells, which release cyt...

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Bibliographic Details
Main Authors: Judith Sánchez-Ventura, Jesús Amo-Aparicio, Xavier Navarro, Clara Penas
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Neuroinflammation
Subjects:
BET protein
Inflammation
Cytokine
Neuroprotection
Spinal cord injury
Online Access:http://link.springer.com/article/10.1186/s12974-019-1511-7

Internet

http://link.springer.com/article/10.1186/s12974-019-1511-7

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