Role of neutrophil chemoattractant CXCL5 in SARS-CoV-2 infection-induced lung inflammatory innate immune response in an in vivo hACE2 transfection mouse model

Role of neutrophil chemoattractant CXCL5 in SARS-CoV-2 infection-induced lung inflammatory innate immune response in an in vivo hACE2 transfection mouse model

Understanding the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and clarifying antiviral immunity in hosts are critical aspects for the development of vaccines and antivirals. Mice are frequently used to generate animal models of infectious diseases due to their conven...

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Bibliographic Details
Main Authors: Yan Liang, Heng Li, Jing Li, Ze-Ning Yang, Jia-Li Li, Hui-Wen Zheng, Yan-Li Chen, Hai-Jing Shi, Lei Guo, Long-Ding Liu
Format: Article
Language:English
Published: Science Press, PR China 2020-11-01
Series:Zoological Research
Subjects:
sars-cov-2
mouse model
lung infection
ace2
neutrophil
cxcl5
Online Access:http://www.zoores.ac.cn/EN/10.24272/j.issn.2095-8137.2020.118

Internet

http://www.zoores.ac.cn/EN/10.24272/j.issn.2095-8137.2020.118

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