Linking Extracellular Matrix Agrin to the Hippo Pathway in Liver Cancer and Beyond

In addition to the structural and scaffolding role, the extracellular matrix (ECM) is emerging as a hub for biomechanical signal transduction that is frequently relayed to intracellular sensors to regulate diverse cellular processes. At a macroscopic scale, matrix rigidity confers long-ranging effec...

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Bibliographic Details
Main Authors: Sayan Chakraborty, Wanjin Hong
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/2/45