Linking Extracellular Matrix Agrin to the Hippo Pathway in Liver Cancer and Beyond
In addition to the structural and scaffolding role, the extracellular matrix (ECM) is emerging as a hub for biomechanical signal transduction that is frequently relayed to intracellular sensors to regulate diverse cellular processes. At a macroscopic scale, matrix rigidity confers long-ranging effec...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-02-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/10/2/45 |