Practical issues encountered while determining Minimal Clinically Important Difference in Patient-Reported Outcomes

Practical issues encountered while determining Minimal Clinically Important Difference in Patient-Reported Outcomes

Abstract Background Using a real dataset, we highlighted several major methodological issues raised by the estimation of the Minimal Clinically Important Difference (MCID) of a Patient-Reported Outcomes instrument. We especially considered the management of missing data and the use of more than two...

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Bibliographic Details
Main Authors: Pascal Woaye-Hune, Jean-Benoit Hardouin, Paul-Antoine Lehur, Guillaume Meurette, Antoine Vanier
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Health and Quality of Life Outcomes
Subjects:
Minimal clinically important difference
Minimal important difference
Patient-reported outcomes
Methodology
Missing data
Longitudinal modeling
Online Access:http://link.springer.com/article/10.1186/s12955-020-01398-w

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http://link.springer.com/article/10.1186/s12955-020-01398-w

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