Identification of Modulators of HIV-1 Proviral Transcription from a Library of FDA-Approved Pharmaceuticals

Human immunodeficiency virus 1 (HIV-1) is the most prevalent human retrovirus. Recent data show that 34 million people are living with HIV-1 worldwide. HIV-1 infections can lead to AIDS which still causes nearly 20,000 deaths annually in the USA alone. As this retrovirus leads to high morbidity and...

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Bibliographic Details
Main Authors: Gavin C. Sampey, Sergey Iordanskiy, Michelle L. Pleet, Catherine DeMarino, Fabio Romerio, Renaud Mahieux, Fatah Kashanchi
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
HIV
Online Access:https://www.mdpi.com/1999-4915/12/10/1067