Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia
In two recent double-blind clinical trials of fetal ventral mesencephalic cell transplants into the striatum in patients with Parkinson's disease (PD), a significant proportion of the grafted patients developed dyskinetic side effects, which were not seen in the sham operated patients. Comparis...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-03-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996105002536 |