Opposite role of tumor necrosis factor receptors in dextran sulfate sodium-induced colitis in mice.

Opposite role of tumor necrosis factor receptors in dextran sulfate sodium-induced colitis in mice.

Tumor necrosis factor-α (TNF-α) is a key factor for the pathogenesis of inflammatory bowel diseases (IBD), whose function is known to be mediated by TNF receptor 1 (TNFR1) or 2. However, the precise role of the two receptors in IBD remains poorly understood. Herein, acute colitis was induced by dext...

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Bibliographic Details
Main Authors: Ke Wang, Gencheng Han, Yan Dou, Yi Wang, Guijun Liu, Renxi Wang, He Xiao, Xinying Li, Chunmei Hou, Beifen Shen, Renfeng Guo, Yan Li, Yanchun Shi, Guojiang Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3532169?pdf=render

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http://europepmc.org/articles/PMC3532169?pdf=render

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