Nano-Strategies to Target Breast Cancer-Associated Fibroblasts: Rearranging the Tumor Microenvironment to Achieve Antitumor Efficacy

Nano-Strategies to Target Breast Cancer-Associated Fibroblasts: Rearranging the Tumor Microenvironment to Achieve Antitumor Efficacy

Cancer-associated fibroblasts (CAF) are the most abundant cells of the tumor stroma and they critically influence cancer growth through control of the surrounding tumor microenvironment (TME). CAF-orchestrated reactive stroma, composed of pro-tumorigenic cytokines and growth factors, matrix componen...

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Bibliographic Details
Main Authors: Marta Truffi, Serena Mazzucchelli, Arianna Bonizzi, Luca Sorrentino, Raffaele Allevi, Renzo Vanna, Carlo Morasso, Fabio Corsi
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
cancer-associated fibroblasts
tumor microenvironment
nanoparticles
breast cancer
antitumor efficacy
Online Access:http://www.mdpi.com/1422-0067/20/6/1263

Internet

http://www.mdpi.com/1422-0067/20/6/1263

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