SID-1 Domains Important for dsRNA Import in Caenorhabditis elegans

In the nematode Caenorhabditis elegans, RNA interference (RNAi) triggered by double-stranded RNA (dsRNA) spreads systemically to cause gene silencing throughout the organism and its progeny. We confirm that Caenorhabditis nematode SID-1 orthologs have dsRNA transport activity and demonstrate that th...

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Bibliographic Details
Main Authors: Jennifer S. Whangbo, Alexandra S. Weisman, Jeiwook Chae, Craig P. Hunter
Format: Article
Language:English
Published: Oxford University Press 2017-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.300308