BETEL LEAF EXTRACTS (PIPER BETLE L.) PREVENT ENDOTHELIAL DYSFUNCTION BY REDUCING THE LEVELS OF URIC ACID AND ICAM-1 EXPRESSION OF THE HYPERURICEMIA WISTAR RATS (RATTUS NORVEGICUS) AORTIC ENDOTHELIAL

<p>Hyperuricemia as a risk factor for cardiovascular disease causes endothelial dysfunction by increasing oxidative stress and inflammation. Extracts of betel leaf (<em>Piper betle L.</em>) contain bioactivity as an antioxidant, anti-inflammatory and XO inhibitor. The aim of the re...

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Bibliographic Details
Main Authors: Made Sumarya, Nyoman Adiputra, Putra Manuaba, Dewa Sukrama
Format: Article
Language:English
Published: Universitas Udayana 2016-01-01
Series:Indonesia Journal of Biomedical Science
Subjects:
Online Access:https://ijbs-udayana.org/index.php/ijbs/article/view/22