Discovery of the Involvement in DNA Oxidative Damage of Human Sperm Nuclear Basic Proteins of Healthy Young Men Living in Polluted Areas

Discovery of the Involvement in DNA Oxidative Damage of Human Sperm Nuclear Basic Proteins of Healthy Young Men Living in Polluted Areas

DNA oxidative damage is one of the main concerns being implicated in severe cell alterations, promoting different types of human disorders and diseases. For their characteristics, male gametes are the most sensitive cells to the accumulation of damaged DNA. We have recently reported the relevance of...

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Bibliographic Details
Main Authors: Gennaro Lettieri, Giovanni D’Agostino, Elena Mele, Carolina Cardito, Rosa Esposito, Annalinda Cimmino, Antonella Giarra, Marco Trifuoggi, Salvatore Raimondo, Tiziana Notari, Ferdinando Febbraio, Luigi Montano, Marina Piscopo
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
DNA oxidative damage
protein–DNA binding
human protamines
heavy metals
EMSA
fluorescence
Online Access:https://www.mdpi.com/1422-0067/21/12/4198

Internet

https://www.mdpi.com/1422-0067/21/12/4198

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