Monte-Carlo modeling of the central carbon metabolism of Lactococcus lactis: insights into metabolic regulation.

Metabolic pathways are complex dynamic systems whose response to perturbations and environmental challenges are governed by multiple interdependencies between enzyme properties, reactions rates, and substrate levels. Understanding the dynamics arising from such a network can be greatly enhanced by t...

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Bibliographic Details
Main Authors: Ettore Murabito, Malkhey Verma, Martijn Bekker, Domenico Bellomo, Hans V Westerhoff, Bas Teusink, Ralf Steuer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182131?pdf=render