Efficient S-Acylation of Thiourea

Efficient S-Acylation of Thiourea

Abstract Efficient S-acylation of thiourea using a variety of acid chlorides is reported. Structurally diverse aryl and alkyl substrates are compatible with this methodology. Confirmation that acylation occurs exclusively­ on the sulfur atom of thiourea is provided by single-crystal X-ray crystallog...

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Bibliographic Details
Main Authors: David J. Jones, Uday B. Rao Khandavilli, Eileen M. O’Leary, Simon E. Lawrence, Timothy P. O’Sullivan
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2018-10-01
Series:SynOpen
Subjects:
isothiourea
thiourea
organosulfur
sulfur transfer
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1610370

Internet

http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1610370

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