Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice.

BACKGROUND: Sleeping sickness due to Trypanosoma brucei (T.b.) gambiense is still a major public health problem in some central African countries. Historically, relapse rates around 5% have been observed for treatment with melarsoprol, widely used to treat second stage patients. Later, relapse rates...

Full description

Bibliographic Details
Main Authors: Patient Pati Pyana, Ipos Ngay Lukusa, Dieudonné Mumba Ngoyi, Nick Van Reet, Marcel Kaiser, Stomy Karhemere Bin Shamamba, Philippe Büscher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3079580?pdf=render