Homodimerization of the death-associated protein kinase catalytic domain: development of a new small molecule fluorescent reporter.

Homodimerization of the death-associated protein kinase catalytic domain: development of a new small molecule fluorescent reporter.

Death-Associated Protein Kinase (DAPK) is a member of the Ca2+/calmodulin regulated serine/threonine protein kinases. Its biological function has been associated with induced cell death, and in vivo use of selective small molecule inhibitors of DAPK catalytic activity has demonstrated that it is a p...

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Bibliographic Details
Main Authors: Michael Zimmermann, Cédric Atmanene, Qingyan Xu, Laetitia Fouillen, Alain Van Dorsselaer, Dominique Bonnet, Claire Marsol, Marcel Hibert, Sarah Sanglier-Cianferani, Claire Pigault, Laurie K McNamara, D Martin Watterson, Jacques Haiech, Marie-Claude Kilhoffer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2994711?pdf=render

Internet

http://europepmc.org/articles/PMC2994711?pdf=render

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