The atonal proneural transcription factor links differentiation and tumor formation in Drosophila.

The acquisition of terminal cell fate and onset of differentiation are instructed by cell type-specific master control genes. Loss of differentiation is frequently observed during cancer progression, but the underlying causes and mechanisms remain poorly understood. We tested the hypothesis that mas...

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Bibliographic Details
Main Authors: Wouter Bossuyt, Natalie De Geest, Stein Aerts, Iris Leenaerts, Peter Marynen, Bassem A Hassan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-02-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2652389?pdf=render