The atonal proneural transcription factor links differentiation and tumor formation in Drosophila.
The acquisition of terminal cell fate and onset of differentiation are instructed by cell type-specific master control genes. Loss of differentiation is frequently observed during cancer progression, but the underlying causes and mechanisms remain poorly understood. We tested the hypothesis that mas...
Main Authors: | Wouter Bossuyt, Natalie De Geest, Stein Aerts, Iris Leenaerts, Peter Marynen, Bassem A Hassan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-02-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC2652389?pdf=render |
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