Altered inhibition and excitation in neocortical circuits in congenital microcephaly

Congenital microcephaly is highly associated with intellectual disability. Features of autosomal recessive primary microcephaly subtype 3 (MCPH3) also include hyperactivity and seizures. The disease is caused by biallelic mutations in the Cyclin-dependent kinase 5 regulatory subunit-associated prote...

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Bibliographic Details
Main Authors: Sami Zaqout, Kathrin Blaesius, Yuan-Ju Wu, Stefanie Ott, Nadine Kraemer, Lena-Luise Becker, Marta Rosário, Christian Rosenmund, Ulf Strauss, Angela M. Kaindl
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119301226