Poly(ADP-Ribose) Polymerase 1: Cellular Pluripotency, Reprogramming, and Tumorogenesis

Poly(ADP-Ribose) Polymerase 1: Cellular Pluripotency, Reprogramming, and Tumorogenesis

Poly(ADP-ribos)ylation (PARylation) is the catalytic function of the Poly(ADP-ribose) polymerases (Parps) family for post-translational modification in cellular process. Being a major member of Parps, Parp1 is a crucial nuclear factor with biological significance in modulating DNA repair, DNA replic...

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Bibliographic Details
Main Authors: Bo-Hua Jiang, Wei-Lien Tseng, Hsin-Yang Li, Mong-Lien Wang, Yuh-Lih Chang, Yen-Jen Sung, Shih-Hwa Chiou
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:International Journal of Molecular Sciences
Subjects:
Parp1
PARylation
pluripotency
reprogramming
tumorogenesis
Online Access:http://www.mdpi.com/1422-0067/16/7/15531

Internet

http://www.mdpi.com/1422-0067/16/7/15531

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