Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells.

Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells.

Prostate cancer is the second leading cause of cancer related death in American men. Development and progression of clinically localized prostate cancer is highly dependent on androgen signaling. Metastatic tumors are initially responsive to anti-androgen therapy, however become resistant to this re...

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Bibliographic Details
Main Authors: Nagireddy Putluri, Ali Shojaie, Vihas T Vasu, Srilatha Nalluri, Shaiju K Vareed, Vasanta Putluri, Anuradha Vivekanandan-Giri, Jeman Byun, Subramaniam Pennathur, Theodore R Sana, Steven M Fischer, Ganesh S Palapattu, Chad J Creighton, George Michailidis, Arun Sreekumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3138744?pdf=render

Internet

http://europepmc.org/articles/PMC3138744?pdf=render

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