The Impacts of Sortase A and the 4′-Phosphopantetheinyl Transferase Homolog Sfp on Streptococcus mutans Extracellular Membrane Vesicle Biogenesis

The Impacts of Sortase A and the 4′-Phosphopantetheinyl Transferase Homolog Sfp on Streptococcus mutans Extracellular Membrane Vesicle Biogenesis

Extracellular membrane vesicles (EMVs) are produced by many Gram-positive organisms, but information regarding vesiculogenesis is incomplete. We used single gene deletions to evaluate the impacts on Streptococcus mutans EMV biogenesis of Sortase A (SrtA), which affects S. mutans EMV composition, and...

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Bibliographic Details
Main Authors: Joyce C. Morales-Aparicio, Patricia Lara Vasquez, Surabhi Mishra, Ana L. Barrán-Berdón, Manasi Kamat, Kari B. Basso, Zezhang T. Wen, L. Jeannine Brady
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Microbiology
Subjects:
vesicles
membrane
proteome
lipidome
Streptococcus mutans
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.570219/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.570219/full

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