Ibogaine Blocks Cue- and Drug-Induced Reinstatement of Conditioned Place Preference to Ethanol in Male Mice

Ibogaine Blocks Cue- and Drug-Induced Reinstatement of Conditioned Place Preference to Ethanol in Male Mice

Ibogaine is a psychedelic extracted from the plant Tabernanthe iboga Baill. (Apocynaceae), natural from Africa, and has been proposed as a potential treatment for substance use disorders. In animal models, ibogaine reduces ethanol self-administration. However, no study to date has investigated the e...

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Bibliographic Details
Main Authors: Gabrielle M. Henriques, Alexia Anjos-Santos, Isa R. S. Rodrigues, Victor Nascimento-Rocha, Henrique S. Reis, Matheus Libarino-Santos, Thaísa Barros-Santos, Thais S. Yokoyama, Natalia B. Bertagna, Cristiane A. Favoretto, Célia R. G. Moraes, Fábio C. Cruz, Paulo C. R. Barbosa, Eduardo A. V. Marinho, Alexandre J. Oliveira-Lima, Laís F. Berro
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
ibogaine
ethanol
conditioned place preference
mice
reinstatement
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.739012/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.739012/full

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