Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry[S]

Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry[S]

Lysophosphatidic acid (LPA) activates cognate G protein-coupled receptors (GPCRs) to initiate biological signaling cascades. Lysophospholipid (LP) receptor binding properties remain incompletely assessed because of difficulties with ligand lipophilicity and lipid “stickiness.” These inherent attribu...

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Bibliographic Details
Main Authors: Hirotaka Mizuno, Yasuyuki Kihara, Amanda Kussrow, Allison Chen, Manisha Ray, Richard Rivera, Darryl J. Bornhop, Jerold Chun
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Lipid Research
Subjects:
lipid
phospholipids
endocannabinoid
optical measurement
molecular interaction
binding assay
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032678X

Internet

http://www.sciencedirect.com/science/article/pii/S002222752032678X

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