A combined computational and structural model of the full-length human prolactin receptor

The prolactin receptor consists of a folded extracellular domain, a transmembrane domain and an intracellular intrinsically disordered domain. Here the authors use a combined experimental and computational approach to obtain a structure of a class I cytokine receptor, the human prolactin receptor.

Bibliographic Details
Main Authors: Katrine Bugge, Elena Papaleo, Gitte W. Haxholm, Jonathan T. S. Hopper, Carol V. Robinson, Johan G. Olsen, Kresten Lindorff-Larsen, Birthe B. Kragelund
Format: Article
Language:English
Published: Nature Publishing Group 2016-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11578