Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.

Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.

Liver disease is a leading contributor to morbidity and mortality during HIV infection, despite the use of combination antiretroviral therapy (cART). The precise mechanisms of liver disease during HIV infection are poorly understood partially due to the difficulty in obtaining human liver samples as...

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Bibliographic Details
Main Authors: Bridget S Fisher, Richard R Green, Rachel R Brown, Matthew P Wood, Tiffany Hensley-McBain, Cole Fisher, Jean Chang, Andrew D Miller, William J Bosche, Jeffrey D Lifson, Maud Mavigner, Charlene J Miller, Michael Gale, Guido Silvestri, Ann Chahroudi, Nichole R Klatt, Donald L Sodora
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006871

Internet

https://doi.org/10.1371/journal.ppat.1006871

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