Calcium-Mediated Oscillation in Membrane Potentials and Atrial-Triggered Activity in Atrial Cells of Casq2R33Q/R33Q Mutation Mice

Calcium-Mediated Oscillation in Membrane Potentials and Atrial-Triggered Activity in Atrial Cells of Casq2R33Q/R33Q Mutation Mice

Aim: We investigated the underlying mechanisms in atrial fibrillation (AF) associated with R33Q mutation and Ca2+-triggered activity.Methods and Results: We examined AF susceptibility with intraesophageal burst pacing in the sarcoplasmic reticulum (SR) Ca2+ leak model calsequestrin 2 R33Q (Casq2R33Q...

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Bibliographic Details
Main Authors: Jian-cheng Zhang, Hong-lin Wu, Qian Chen, Xiao-ting Xie, Tian Zou, Chao Zhu, Ying Dong, Guo-jian Xiang, Lei Ye, Yang Li, Peng-li Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physiology
Subjects:
Ca2+-triggered activity
AF
SCaE
oscillation in membrane potentials
EADs/DADs
ITi
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01447/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01447/full

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