Determination of major UDP-glucuronosyltransferase enzymes and their genotypes responsible for 20-HETE glucuronidation[S]

Determination of major UDP-glucuronosyltransferase enzymes and their genotypes responsible for 20-HETE glucuronidation[S]

The compound 20-HETE is involved in numerous physiological functions, including blood pressure and platelet aggregation. Glucuronidation of 20-HETE by UDP-glucuronosyltransferases (UGTs) is thought to be a primary pathway of 20-HETE elimination in humans. The present study identified major UGT enzym...

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Bibliographic Details
Main Authors: Yazun Bashir Jarrar, Eun-Young Cha, Kyung-Ah Seo, Jong-Lyul Ghim, Hyo-Ji Kim, Dong-Hyun Kim, Su-Jun Lee, Jae-Gook Shin
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Journal of Lipid Research
Subjects:
20-hydroxyeicosatetraenoic acid
uridine diphosphate-glucuronosyltransferase
genetic polymorphisms
arachidonic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520349853

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http://www.sciencedirect.com/science/article/pii/S0022227520349853

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