Autoantibodies to estrogen receptor α in systemic sclerosis (SSc) as pathogenetic determinants and markers of progression.

Systemic sclerosis (SSc) is a multisystem autoimmune disease of unknown etiology characterized by inflammation, autoantibody production, and fibrosis. It predominantly affects women, this suggesting that female sex hormones such as estrogens may play a role in disease pathogenesis. However, up to da...

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Bibliographic Details
Main Authors: Antonello Giovannetti, Angela Maselli, Tania Colasanti, Edoardo Rosato, Felice Salsano, Simonetta Pisarri, Ivano Mezzaroma, Walter Malorni, Elena Ortona, Marina Pierdominici
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24058548/pdf/?tool=EBI