The piRNA pathway responds to environmental signals to establish intergenerational adaptation to stress

Abstract Background piRNAs have a constitutive role in genome defence by silencing transposable elements in the germline. In the nematode Caenorhabditis elegans, piRNAs also induce epigenetic silencing of transgenes, which can be maintained for many generations in the absence of the piRNA pathway. T...

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Bibliographic Details
Main Authors: Tony Belicard, Pree Jareosettasin, Peter Sarkies
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Biology
Online Access:http://link.springer.com/article/10.1186/s12915-018-0571-y