Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites

Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites

Objective: In the present study, we investigated the effects of dextromethorphan (DM) and its metabolites, including dextrorphan (LK2), 3-methoxymorphinan (LK3), and 3-hydroxymorphinan (LK4), on platelet aggregationin vitro and the inflammatory pain caused by carrageenan in rats, and their underlyin...

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Bibliographic Details
Main Authors: Wen-Lin Su, Yu-Ya Weng, Wen-Hsin Huang, Hao-Ai Shui, Tz-Chong Chou
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Tzu-Chi Medical Journal
Subjects:
carrageenan
dextromethorphan
inflammatory pain
metabolites
platelet aggregation
Online Access:http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2020;volume=32;issue=2;spage=154;epage=161;aulast=Su

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http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2020;volume=32;issue=2;spage=154;epage=161;aulast=Su

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