P38 MAP Kinase Mediates Apoptosis After Genipin Treatment in Non–Small-Cell Lung Cancer H1299 Cells via a Mitochondrial Apoptotic Cascade

Abstract.: Genipin, an active constituent of Gardenia fruit, has been reported to show an antitumor effect in several cancer cell systems. Here, we demonstrate how genipin exhibits a strong apoptotic cell death effect in human non–small-cell lung cancer H1299 cells. Genipin-mediated decrease in cell...

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Bibliographic Details
Main Authors: Xue Yang, Jie Yao, Yue Luo, Yongguang Han, Zuobai Wang, Linfang Du
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S134786131930355X