Improved statistical methods enable greater sensitivity in rhythm detection for genome-wide data.

Robust methods for identifying patterns of expression in genome-wide data are important for generating hypotheses regarding gene function. To this end, several analytic methods have been developed for detecting periodic patterns. We improve one such method, JTK_CYCLE, by explicitly calculating the n...

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Bibliographic Details
Main Authors: Alan L Hutchison, Mark Maienschein-Cline, Andrew H Chiang, S M Ali Tabei, Herman Gudjonson, Neil Bahroos, Ravi Allada, Aaron R Dinner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4368642?pdf=render