Hedgehog Signaling in Lung Cancer: From Oncogenesis to Cancer Treatment Resistance

Hedgehog Signaling in Lung Cancer: From Oncogenesis to Cancer Treatment Resistance

Hedgehog signaling pathway is physiologically activated during embryogenesis, especially in lung development. It is also reactivated in many solid tumors. In lung cancer, Hedgehog pathway is closely associated with cancer stem cells (CSCs). Recent works have shown that CSCs produced a full-length So...

Full description

Bibliographic Details
Main Authors: Etienne Giroux-Leprieur, Adrien Costantini, Vivianne W. Ding, Biao He
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
Sonic Hedgehog
lung cancer
oncogenesis
cancer stem cell
chemoresistance
Epidermal Growth Factor Receptor (EGFR)
tyrosine kinase inhibitor
radiotherapy
immune checkpoint inhibitor
Online Access:http://www.mdpi.com/1422-0067/19/9/2835

Internet

http://www.mdpi.com/1422-0067/19/9/2835

Similar Items