Clustering gene expression time series data using an infinite Gaussian process mixture model.

Transcriptome-wide time series expression profiling is used to characterize the cellular response to environmental perturbations. The first step to analyzing transcriptional response data is often to cluster genes with similar responses. Here, we present a nonparametric model-based method, Dirichlet...

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Bibliographic Details
Main Authors: Ian C McDowell, Dinesh Manandhar, Christopher M Vockley, Amy K Schmid, Timothy E Reddy, Barbara E Engelhardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5786324?pdf=render